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"A novel and efficient nicotine vaccine using nano-lipoplex as a…
"A novel and efficient nicotine vaccine using nano-lipoplex as a delivery vehicle"
Dr. Chenming "Mike" Zhang
Problem
Tobacco
smoking
cigarettes
kills millions :skull:
6 M (2011)
economy :money_with_wings:
nicotine
smoking trends :smoking:
1B people dead :skull:
projected
21st cen.
addiction
dopamine
deaths
Larger Issue
pharmacological aids :female-doctor::skin-tone-2:
replacement therapy
bupropion
varenicline
short-term :hourglass:
relapse :arrows_counterclockwise:
ineffective :red_cross:
Investigation
immune system
antibodies
virus
bacteria
proteins
vaccine?
anti-nicotine
new antibodies
molar ratios
nicotine
molecules
haptens
carrier proteins
experiement
animal studies :rat:
human trials :silhouette:
Solutions :+1:
vaccine
anti-nicotine
antibodies
immune system
long-term solution :timer_clock:
no relapse
brain
no access
no dopamine
no addiction
New Problems :!?:
only carrier proteins
too small
more studies
cleared by RES
ligands
limited
delivery systems
must increase :arrow_up:
antigen
hapten capacity
cationic liposomes