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Necrotizing fasciitis, Infection of muscle fascia, Pathology - Coggle…
Necrotizing fasciitis
Infection of muscle fascia
Local immune response
Production endotoxins by bacteria
Blood clots in vessel
Tissue ichemia
Destruction of peripheral nerve
Pain
Tissue hypoxia
anaerobic metabolism
Serum lactate
Tissue death
Build up of gas in subcutaneous
Crepitus
Release cytokines into the bood
Capillary vasodilator
Blood flow to tissue
Warm/Erythema
Fluid and protein shift from cell and capillary space
Edema
Compartment syndrome
Blood vessel dilation
Perfusion of vital organs
Heart rate to perfusion
Tachycardia
Poor perfusion of lungs impair gas exchange
Tachypnea
Acute Kidney injury
Oligurea
Electrolytes imbalance
Metabolic acidosis
Hypotension
Systemic immune response
Pyrogen to the blood stream to hypothalamus alter set point
Fever
Bone marrow
WBC
Transmission bacteria from tissue infection to blood
Sepsis
Pathology