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Non-infectious skin diseases - Coggle Diagram
Non-infectious skin diseases
atopic dermatitis
urticaria
Urticarial lesions are circumscribed, raised, erythematous plaques, often with central pallor
Pruritus ➔ They are intensely itchy
usually appearing and enlarging over the course of minutes to hours and then disappearing within 24 hours
➔ Pathophysiology
Urticaria is mediated by cutaneous mast cells in the superficial dermis
► Upon activation, mast cells and basophils release multiple mediators (including histamine) which causes the localized swelling, vasodilation (redness) and itching
➔ Etiologies
► Infections (parasitic, viral and bacterial infections)
► IgE-mediated allergic reactions (type 1 immediate allergic reactions)
► NSAIDs - such as aspirin and ibuprofen
➔ Systemic disorders that may include urticaria.
❖Mastocytosis and mast cell disorders
❖Systemic lupus erythematosus,
rheumatoid arthritis, Sjögren syndrome, celiac disease, autoimmune thyroid
disease, and other autoimmune diseases
➔ Treatment
chronic urticaria, 2nd generation (non-sedative) H1 antihistaminics can be given
► E.g., cetirizine
❖ Glucocorticoids are necessary for isolated urticaria
seborrheic dermatitis
CHRONIC inflammatory dermatoses w/high density of sebaceous glands
INFLAMMATION of the EPIDERMIS
SYMPTOMS:
Cradle cap: Erytje,aypus scaly eruption on scalp
happens in first 2months and then again in adolescence
INFANT: Asymotomatic, can spread to flexual areas
ADOLESCENTS: typically as dandruff, periocular redness
In contrast to eczema ➔ this is not very itchy
Pathophysiology
increased sebum production in response to androgens
❖Also, a fungus - Malassezia furfur - will grow in that area
TREATMENT
self-limited course and resolves spontaneously in weeks to several months
other than the scalp ➔ ketoconazole 2% cream or a low-potency
corticosteroid cream
hemangiomas
Infantile
Capillary
Pyogenic granulomas
Cavenous