A 5-year-old girl comes with a complaint of fever and cough since 5 days. Currently, redness appears on the skin but is not accompanied by itching. The patient also complained of both red and watery eyes since 1 day ago. On physical examination, pulse 100x/m, RR 28x/m, Tax 38.8C, found ODS conjunctivitis and gross maculopapular erythema on the face, neck, trunk and extremities. Other examination results were within normal limits.
Fever Measles
Etiology
Measles Fever is caused by paramyxovirus, a virus with a single strand RNA that has a single type of antigen.
Pathogenesis
The first cell that got infected is monocyte. leucocyte cell can be infected to spread the infection.
Pathophysiology
A substance called pyrogen. pyrogen can be classified into 2, Exogenous and endogenous. Exogenous pyrogen is pyrogen that came from outside the human body. Endogenous pyrogen is pyrogen that came from inside the human body
Maculopapular Erythema
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Pathogenesis
The eruption starts from behind the ear and the border head hair then spreads centrifugally throughout the body 3rd day of exanthema. Exanthema in the form of well-defined erythematous papules and then confluent into larger patches, not itchy
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ODS conjunctivitis
Pathophysiology
measles came from respiratory tract and stick to the epithelial cell of respiratory system. Attached virus began to replicate and spreads to regional lymph node.
Pathogenesis
Adhesion, Evasion, and Invasion
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Complications
Respiratory tract, Gastrointestinal tract, Ear
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