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DIURETIC : image , - Coggle Diagram
DIURETIC :
CARBONIC ANHYDROUS
SITE OF ACTION : proximal tubule of the nephron and red blood cells.
MOA :
CO2 + H2O H2CO3 H + HCO3
💊Drugs
ETHOXZOLAMIDE
BRINZOLAMIDE
METHAZOLAMIDE
ACETAZOLAMIDE
LOOP OF DIURETIC
SITE OF ACTION :thick ascending limb (TAL) of the loop of Henle
PHENOXYACETIC ACID DERIVATIVES
ETHACRYNIC ACID
SULPHAMOYL ANTHRANILIC ACIDS
FUROSEMIDE
BUMETANIDE :
MOA : inhibit the luminal Na+/K+/2Cl− symporter.
THIAZIDE /BENZOTHIADIAZIE
SITE OF ACTION : Distal convoluted tubule of the nephron
MOA : Na+/Cl– symporter and
inhibit the reabsorption of sodium and chloride ions
DRUG💊
HYDROFLUMETHIAZIDE
CYCLOTHIAZIDE
HYDROCHLORTHIAZIDE
CHLORTHIAZIDE
Osmotic diuretic :
SITE OF ACTION :descending limb
of the Loop of Henle;
MOA: inhibit water reabsorption in the thin descending loop of Henle and collecting duct, regions of the kidney that are highly permeable to water
💊DRUGS
MANNITOL
Aldosteron antagonist
SITE OF ACTION : block the action of aldosterone
DRUG💊:SPIRONOLACTONE
DRUG💊: EPLERENONE
RENAL EPITHELIAL SODIUM CHANNEL BLOCKERS
SITE OF ACTION : ENaC inhibitors block these channels and inhibit the reabsorption of sodium.
AMINOPYRAZINE : amiloride
PTERIDINE : triamterene
MOA :
