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Enzymes - Coggle Diagram

- - - - Temp ↑, ROR ↑ until a certain point until optimum temp is reached. But ROR ↓ rapidly when Temp ↑ beyond optimum temp
      - Graph: Fig 63 of https://tinyurl.com/BioIP3
    - - 1) Temp ↑, KE of enzyme and substrate molecules ↑.
      - 2) ↑ no. of effective collisions between enzyme and substrate molecules
      - 3) More Enzyme-Substrate Complexes formed per unit time, hence ROR ↑
      - 4) Temp ↑ beyond optimum, intra-molecular bonds that stabilise tertiary and quaternary structures of protein disrupted
      - 5) Enzyme unfolds, precise active site shape lost
      - 6) Enzyme denatured, no longer binds to substrate molecules, hence ROR ↓