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Intraepithelial lymphocytes, Function Which cell do they influence How…

- - - - Reacts with E-cadherin on enterocytes
        Faciliates entry and retention in intestinal epithelium
    - - Reacts with CCL25 (produced by IEC)
        Thereby recruits IEL
        
        Homing function
    - - Homodimer
      - Not as co-recepter
        Influences their functional characteristics
      - CD8αα
        
        TL antigen
        
        Repress partially activated lymphocytes
        
        Most common cell types
- - - - Derived from antigen-experienced, conventional Tcells
        
        Home immediately after development
        
        Memory cells
    - - Home immediately after development
    - - CD8 recognizes MHCI, infected cells
      - CD4 recognizes MHCII, APCs