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CD4+ - Coggle Diagram
CD4+
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Th2
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Function
The TH2 subset responds to parasite infections by secreting cytokines that activate mast cells, basophils, and eosinophils. The mediators released by these cells induce contractions of smooth muscle that eject parasitic worms and protozoans from the gut and respiratory tracts. These same mechanisms cause the allergic reactions to pollen, nickel, and other harmless substances.
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Th1
Function
The TH1 subset of helper T cells activates macrophages to increase phagocytosis and to kill those phagocytosed pathogens that resist the usual processes of intracellular degradation
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Tfh
Function
Cytokines secreted by TFH cells induce the differentiation of antigen-activated B cells to become antibody-secreting plasma cells.
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Treg
Function
Treg cells closes down the effector CD4 and CD8 T-cell responses to prevent further inflammation and tissue damage.
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