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MHC - Coggle Diagram
MHC
MHC II
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Synthesized in the ER, entrance is facilitated by TAP protein
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Expressed by professional antigen presenting cells
Macrophage, dendritic cell, B cell
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Encoded by HLA-DP, HLA-DQ, HLA-DR Genes
Two polymorphic subunits - Alpha and Beta, which causes more variations due to the intraisotype combinations from the paternal and maternal haplotypes.
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Comes from the HLA gene
Inheritance of HLA is cross-linked, meaning 25% chance for each combination of paternal and maternal genes
MHC I
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Encoded by HLA-A, HLA-B, HLA-C Genes
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