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Intraepithelial Leukocytes, Innate Lymphoid Cells, Natural, γδ T cells -…
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Innate Lymphoid Cells
ILC3
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Interact wirh DC cells (IL-23), which stimulates IL-22 production by ILCs
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respond to extracellular pathogens and participate in the containment of commensal microorganisms in the gut
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ILC2
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Response against helminths. The by helminth killed cells release alarmins such as IL-25 and IL-33. Il-25 incudes IL-13 production in ILC2, which is a mediator for mucous production. It also activates DC cells with IL-13. With IL-5 they recruite eosinophils and mast cells and induce muscle contraction. In response to IL-33, they also release amphiregulin. This induces tissue repair following the helminth clearancd
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ILC do not express adaptive antigen recognition receptors. Activation is regulated by cytokines, rather than antigen recognition.
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