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Biology Summer HW - Coggle Diagram
Biology Summer HW
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Health and disease
Communicable disease = those which can be transferred between individuals through methods such as coughing and drinking the same water.
Non-communicable disease = those which cannot be transferred between individuals such as genetic disorders, asthma and diabetes.
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Phagocytosis is the process of white blood cells (phagocytes) engulfing/consuming pathogens which no longer make you feel ill.
Producing antibodies - Each pathogen has an antigen on its surface which is a structure where a specific complementary antibody can bind to. Once antibodies begin to bind to the pathogen, the pathogens start to clump together, resulting in it being easier for the white blood cells to find them and engulf them in phagocytosis.
During this process, the antigens also trigger production of memory lymphocytes. If you become infected again with the same pathogen, the specific complementary antibodies will be produced at a faster rate. The individual will not feel the symptoms of the illness.
Immunisation
A vaccine contains a dead or inactive form of the pathogen which is injected into a patient. This stimulates white blood cells to produce antibodies complementary to the antigens on the pathogen, thus making the patient immune.
Developing new medicine
Preclinical testing - using cells, tissues and live animals.
Clinical testing - the drug is tested on patients/volunteers. First, they are tested on healthy volunteers with a low dose to ensure there are no harmful side effects. They are then tested on patients to find out the most effective dose
To test how well it works, patients are split into two groups with one group receiving the drug and one receiving a placebo. (does not contain the active ingredient).
These can be single blind (only the doctor knows which one is real or which is fake) or double blind (patient and doctor both don't know which is the placebo and which is the real drug to eliminate any bias in the results).
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Key concepts in Biology
Animal/plant cells are eukaryotic. They have: Cell membrane, cytoplasm and nucleus.
Bacteria cells are prokaryotic. They have: Cell wall, cell membrane, cytoplasm, singular circular strand of DNA and plasmids.
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Enzymes are biological catalysts. They help speed up reactions in the body but aren't used up in the process. They work by binding together with a complementary substrate that fits the shape of their active site.
This is known as the lock and key hypothesis. 1) shape of substrate is complementary to the shape of the active site on an enzyme, so when they bind together it forms an enzyme-substrate complex. 2) once bound, the reaction takes place and the products are released from the surface of the enzyme.
As substrate concentration increases, a saturation point is met where increasing the concentration of substrates will have no effect on the rate of reaction because all of the active sites are full.
An optimum temperature and pH are required so that enzymes do not denature (lose the shape of their active site, when this happens an enzyme-substrate complex can no longer be formed so a chemical reaction cannot be sped up)
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Magnification of a light microscope = Magnification of the eyepiece lens x magnification of the objective lens
Formula triangle for magnification
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Cells and Control
Stem cells = undifferentiated cell which can undergo division to produce similar cells, some of which will have different functions.
Types of stem cells
Adult stem cells - found in bone marrow, they can form many types of cells e.g blood cells, but are unable to form every type of cell.
Meristem in plants - Found in shoots/root tips. They can differentiate into any type of cell and the plant can use them throughout its entire life.
Embryonic stem cells - formed when a zygote is created. Can differentiate into any type of cell in the body.
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