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Magnesium - Coggle Diagram
Magnesium
Hoemeostasis
2nd most important intracellular cation
Total body <1000mmol
average daily requireemnt <0.1mmol/kg/day
Absorbed Small intestine (increased by PTH)
50-60% in bone
Renal excretion increased
aldosterone
hypercalcaemia
urinary flow
Function
enzymatic
DNA,RNA and protein synthesis
Calciu antagonist
Hypomagnesaemia
Causes
Renal loss
Hyperaldosteronism /volume expanded states
Hyperparathyroidism
HYpercalcaemia
Polyuric phase of AKI
Diuretics
Aminoglycosides
Alcohol
Balnace
Refeeding syndrome
Phosphate depletion
GI loss
D+V
Short bowel syndrome
Pancreatitis
Symptoms
GI
Neuromuscular hyperactivity
Neurological disturbance
ECG
Prolonged QTc
Prolonged PR
T wave inversion
U waves
SVT
VT
Management
10-20mmol Mg
Hypermagnesimia
Symptoms
Neurological weakness
Loss of tendon reflexes
GI symptoms
ECG
Prolonged PR
Wide QRS
AV block
Bradyarrythmias
Cardiac arrest
Treatment
Calcium chloride