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Haematological Malignancy - Coggle Diagram
Haematological Malignancy
Neutropenic sepsis
NICE CG151
<0.5 absolute count
Tempreture
Infection
Management
Reverse barrier nursing
positive pressure side room
Aviod invasive procedures
Avoid rectal examination
Meticulous oral hygiene
G-CSF
Antibiotics antipsudomonal beta lactam
Tazocin
Meropenam
Gram neg
aminoglycosides
quinolones
Penicillan allergy
ciprofloxacin
clindamycin
Vancomycin
aztreonam
Tumour Lysis syndrome
Features
K
Acidosis
<Ca
Ph
Acidosis
Renal failure
urate
Management
Fluid
yperkalameia manegement
Rasburicase
recombinant urate oxidase enzyme
Aloopurinol
Graft versus host disease
Acute <100 days
Seattle- Glucksberg staging system
Skin Changes
Bilirubin
GI fluid loss
Stage I-IV
Management
Stage 1 topical corticosteroid
Grade 2 systemic steroids
Grade 3 calcineurin inhibitor
Grade IV additional immunosuppresant eg ciclosporin
Chronic <100 days
scleroderma,
primary biliary cirrhosis
Bronchiolitis obliterans
Chronic immunodeficiency
Typhlitis
Features
nausea
Distensions
abdominal pain
Fever
Neutropenic enterocolitis
Management
Right hemi-colectomy