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BACILLUS SPP. - Coggle Diagram
BACILLUS SPP.
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VIRULENCE FACTORS
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Anthrax toxins
Made up of 3 proteins
Protective antigen (PA)
Protein that binds to specific cell receptors, form membrane channel to: mediate entry of EF n LF into the cell
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CLINICAL MANIFESTATIONS
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Bacillus anthracis
Causes anthrax
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Inhalation anthrax
Begins with airborne endospores, germinate lungs then secrete toxins that absorbed into blood
DIAGNOSTIC LAB TESTS
Specimen
Pus from local lesion, blood,pleural fluid in inhalational anthrax, stool in GI anthrax.
gram positive rods in chains
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