Please enable JavaScript.
Coggle requires JavaScript to display documents.
Nutrition: Vitamins - Coggle Diagram
Nutrition: Vitamins
Lipid Soluble
D
:star: D3 D2 from sun and diet --> 25OH D storage form in liver --> 125 OH D active form in kidney
:no_entry:Rickets/osteomalacia
E
antioxidant --> protect lipids from oxidative damage
:no_entry: hemolytic anemia, retinitis pigmentosa
:check:Enterocolitis in infants
A
:no_entry: Night blindness, xerophtalmia, keratomalacia.
Bitot spots
:check: teratogenic
K
:STAR: Y carboxilation of glutamic acid to prothrombin (II,VII, IX,X, protein C and S)
:no_entry: Neonatal hemorrhage with PT, PTT elevated and normal bleeding time
Essential Fatty Acids
: diet
Omega 3 (linolenic)
Omega 6 (linoleic) :!: Arachidonic Acid
Water soluble
C Ascorbic Acid
:star:collagen synthesis: prolyl and lysyl hydroxylases :star: catecholamine synthesis : dopamine hydroxylase --> dopamine to NE :star: iron absorption Fe2+
:no_entry: Scurvy :check: iron excess, stones
B
B5 Panthotenic acid
:star: Fatty acid metabolism: CoA :star: PDH: phosphate dehydrogenase :star:TCA: a ketoglutarate dehydrogenase
:no_entry: rare
B6 Pyridoxine
PLP :star: Protein catabolism: aminotransferases :star:heme synthesis:
:no_entry: caused by INH --> sideroblastic anemia, cheilosis, convulsions
B3 Niacin
:star: NAD, NADP: dehydrogenase depends vit B2 B6 and tryptophan
:no_entry: Pellagra (Diarrhea, dermatitis, dementia)--> Hartnup disease, INH, malignant carcinoid syndrome
:check: facial flushing, hyperlglucemia, hyperuricemia
B7 Biotin
:star: gluconeogenesis :Pyruvate carboxylase :star: fatty acid synthesis: Acetyl CoA carboxylase :star: fatty acid oxidation: propionyl CoA carboxylase
:no_entry: caused by excess of eggs (avidin): alopecia, bowel inflammation, muscle pain
B2 RiboFlavin
:star: FAD, FMN : dehydrogenases
:no_entry: keilosis, magenta tongue, corneal neovascularization
B9
Folate
: THF :star: thimidine synthesis: thymidylate synthase :star: purine synthesis
:no_entry: caused by alcoholism, pregnancy and hemodyalisis --> homocysteinemia, neural tube defects, megaloblastic anemia :red_flag: phenitoin, metrothexate, sulfonamides
B1 Thiamine:
TPP --> :star: metabolism VIL: Branched chain ketoacid dehydrogenase :star: TCA: a ketoglutarate dehydrogenase :star: glycolisis - TCA --> PDH :star: HMP shunt: transketolase
:no_entry: Wernicke encephalopathy, Korsakoff syndrome, Wernicle korsakoff syndrome, Dry and wet beri beri
B12
Cyanobalamin
:star: cofactor methionine synthase --> homocysteine to methionine :star: Fatty acids odd number: methylmalonul CoA mutase :no_entry: Pernicious anemia, Subacute combined degeneration of nerves