14.1 (RA) Rheumatoid Arthritis
Definition: a chronic systemic autoimmune disease that causes inflammation of connective tissue, primarily in the joints
Pathophysiology
Causes
Manifestations
OA vs. RA
STAGES
Patient Education
Treatment
Diagnostic tests
Nursing diagnosis
- genetic factors
- environmental factors
- role of estrogens
- infectious agent (e.g. mycoplasma, Epstein-Barr virus - may initiating the abnormal immune responses)
- cigarette smoking - increase the risk
- exposure to an unidentified antigen (virus) causes an aberrant immune response in a genetically susceptible host.
- normal antibodies (immunoglobulins) become autoantibodies & attack host tissues -> transformed antibodies
- the self-produced antibodies bind with their target antigens in blood.
- leukocytes from the circulation are attracted to the synovial membrane of involved joints (neutrophils & macrophages ingest the immune complexes & release enzymes that degrade synovial tissue and articular cartilage) -> this increases the inflammatory process.
- the inflammatory processes damage the synovial membrane. It swells and abnormally enlarge.
Stage 2: Presence of x-ray evidence of periarticular osteoporosis, subchondral bone destruction but no joint deformity
Stage 3: X-ray evidence of cartilage and bone destruction in addition to joint deformity and periarticular osteoporosis
Stage 1: No destructive changes on x-rays
Stage 4: Presence of bony or fibrous ankylosis (bone fused together) along with stage 3 features.
joint: inflammation cause inflammation (joint is destroyed -> weakened ligaments, tendons) -> weakened structure can cause deformity
- red, hot, swollen, pain, stiffness in the morning (lasts more than 1 hour), inflammation, fatigue, anorexia, weight loss, aching
- usually affect PIP and MCP
*PIP (proximal interphalangeal)
*MCP (metacarpophalangeal)
OA
RA
- caused by mechanical wear & tear on joints
- affects the small finger joints, thumb and knees
- only affect 1 particular joint/ area of the body
- an autoimmune disease in which the body's own immune system attacks the body's joints
- affect joints all the over the body including hands, fingers, elbows, knees & hips
- affects multiple joints on both sides of the body
Rheumatoid factor: found in the blood of RA pts
- (CRP) C-reactive Protein: elevated due to inflammation. (measures the amount of a certain protein that is produced by the body due to inflammation)
- (ESR) Erythrocyte sedimentation rate: RBCs that settle faster than normal indicate inflammation in the body (measures how fast red blood cells settle in the test tube)
- Anti-CCP antibody: a specific marker for RA (detects antibodies to CCP: cyclic citrullinated peptide)
- (FBC) Full Blood Count: to identify anaemia
- Synovial Fluid examination: demonstrate changes associated with inflammation (increased turbidity- cloudiness, decreased viscosity, increased protein and WBC levels)
- X-ray of affected joints: space narrowing may be seen
- Rest and exercise
- regular rest periods reduce manifestations
- splinting reduces unwanted motion
- low-impact aerobic exercises (swimming, walking)
- Heat and Cold therapy
- used for analgesics and muscle-relaxing effects
- Assistive Devices and splints
- splints provide joint rest, prevent contractures
- Surgery
- for to has failed to prevent joint damage
- Arthrodesis (joint fusion): used to stabilize joints
- Arthroplasty (total joint replacement): for gross deformity and joint destruction
PROMOTE SELF-HEALTH MANAGEMENT
DISTURBED BODY IMAGE
MANAGE CHRONIC PAIN
- Monitor the level of pain and duration of morning stiffness.
(R) Increased pain may necessitate changes in treatment plan. - Teach the use of heat and cold applications to provide pain relief.
(R) Both heat and cold have analgesic effects and can help relieve associated muscle pain. - Teach about the use of prescribed anti-inflammatory medications and the relationship of pain and disease activity.
(R) Anti-inflammatory agents reduce chemical mediators of inflammation and edema, relieving pain.
- Demonstrating a caring, accepting attitude towards the patient. (R) Help pt accept the physical changes.
- Encourage the pt to talk about the effects of the disease, both physical effects and effects on life roles.
(R) Verbalization helps identify the feelings and gives the nurse the opportunity to validate证实 the feelings. - Encourage pt to maintain self-care and usual roles to the extent possible.
(R) Independence enhances self-esteem. - Provide positive feedback for self-care activities and adaptive strategies.
(R) This can encourage pt to continue adaptive measures and maintain independence.
- Assess the pt's understanding of RA, its manifestations and effects, and the anticipated course of the disease. Reinforce and clarify information as needed.
(R) Newly diagnosed pts need understandable information that is readily available to develop an understanding of their disease and its treatment. - Initiate an interprofessional care conference with the pt and family.
(R) Pt and families need opportunities to discuss management strategies and their concerns and perceptions to develop a better understanding of interprofessional team member roles and services. - Refer the pt and family to community & social service agencies and local support groups.
(R) These groups and agencies are valuable resources for the pt and family. - Encourage the pt and family members to discuss the effect of the disease on their lives.
(R) Open discussion helps identify the need for practical skills manage RA.
- Address the disease process & treatments, including rest and exercise.
- Inform pt and family management of stiffness and pain.
- the need for energy conservation
- Inform pt and family of assistive devices to maintain independence, including self-care aids such as handheld showers, long-handles brushes and shoehorns, and eating utensils with oversized/ special handles.
- Teach pt and family on how to apply splints and take care of skin. Highlight the need for home and equipment modifications, such as a raised toilet seat and grab bars in the bathroom.