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metabolism of lipid 2 - Coggle Diagram

- - - - PGH2 synthase in smooth ER
      - PGH2
        Synthase Has Two Isoforms
        
        COX-1
        
        COX-2
        
        NSAIDs Inhibit Cyclooxygenase (COX)
        Activity
        
        Aspirin(irreversible inhibitor)
        
        Ibuprofen and naproxen(competitive inhibitor)
- - - - Statins resemble mevalonate -> competitive
        inhibitors of HMG-CoA reductase
- - - - Glucagon and epinephrine lead to phosphorylation and inactivation of
        ACC
- - - - Six Activated Isoprene Units
        Condense to Form Squalene
    - - Conversion
        of Mevalonate to Activated Isoprenes
    - - Acetyl-CoA to HMG-CoA to Mevalonate