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DNA replication, repair and recombination - Coggle Diagram

- - - - Segments of DNA are rearranged either within a chromosomeor between two DNA molecules (recombination), givingoffspring a novel DNAoffspring a novel DNA
- - - - The Meselson-Stahl Experiment
    - - Cairns’ experiments
  - - - insertion site
      - postinsertion site
    - - There Are at Least Five DNA
        Polymerases in E. Coli
        
        DNA polymerase III : the principal replication
        polymerase
        
        beta clamps:increase the processivity
        
        DNA polymerases II, IV, and V:
        DNA repair
        
        DNA polymerase I
  - - - Requires a prereplicative complex
      - The origin recognition complex (ORC) loads a
        helicase onto the DNA
    - - DNA Pol α - polymerase/primase activity
      - DNA Pol δ (lagging strand) and DNA Pol δ (leading
        strand)
    - - telomere
- - - - cleave N-glycosyl bond
      - create apurinic/apyrimidinic (AP) site
      - Uracil glycosylase removes uracil from DNA
  - - - remove 12–13 nucleotides
    - - remove 27–29 nucleotides