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Macro-anatomy - Coggle Diagram
Macro-anatomy
Cerebral cortex
Frontal lobe
- Voluntary movement
- Personality
- Working memory
- Reward & punishment
Primary motor cortex
- Voluntary movement
- Pre central gyrus
- Homunculus
** Top = feet/legs/groin torso,
bottom = hands/arms/face/tongue
** Larger areas for fine motor
e.g. TMS spasm
-
Broca's area
- No fluent speech
- Inferior frontal gyrus (usually L hemisphere)
e.g. Patient Tan
- Visual processing
e.g. cortical blindness, achromatopsia (cannot see colour), akinetopsia (cannot perceive movement)
Parietal lobe
Somatosensory cortex
- Processes touch/pressure/pain/temp/proprioception
- In post central gyrus
e.g. stimulate cortex
Parietal cortex
- Spatial navigation
e.g. hemispatial neglect
Temporal lobe
- Hearing
- Object recognition & facial perception
- Memory
-
-
Wernike's area
- No language meaning/comprehension
- L hemisphere, between temporal & parietal
Corpus callosum
- Share info with contralateral side
e.g. split for Grand Mal seizure ->
name object in L, not see in R
- Gyri: bumps
- Sulci: depressions (deep = fissures)
- Increased surface area (less space) -> more functions (highly adaptive)
Investigative techniques
Brain injury
- Disease
- Injury
- Limited: imprecise, uncontrolled
Psychosurgery
- Animals: ablation, electrode insertion
- Humans: lesion, DBS
Neuroimaging
Invasive
PET: Positron Emission Tomography
- Injected radioactive 'tracer' that binds to brain molecules
- High spatial, poor temporal
- Use: brain function; diagnose cancer, dementia
Non-invasive
EEG: Electroencephalography
- Electrodes on scalp
- High temporal, low spatial
- Use: evaluate brain disorders (seizure timing, narcolepsy - sleep, psychoses, Alzheimer's)
MRI: Magnetic Resonance Imaging
- Magnetic fields to measure brain/body tissue
- High spatial, (low temporal)
- Use: brain structure; diagnosis (bleeding, swelling, tumours, seizures, strokes)
fMRI: Functional MRI
- Indirect measure - changes in blood levels - BOLD
- Low temporal
- Use: brain function; detect abnormalities (tumours), effect of stroke/disease
Resolution
- Spatial: precise area
- Temporal: how fast
Brain stimulation
Invasive
DBS: Deep Brain Stimulation
- Insert electrodes in brain
- Use: treat Parkinsons, essential tremour, MS
Non-invasive
TMS: Transcranial Magnetic Stimulation
- Electromagnetic field to induce currents in brain
- Use: MDD (depression)
-
Brain
Human brains (vs animals)
- Metabolically expensive
- High EQ (brain size controlled for body size)
- Cerebral cortex well developed
=> evolutionary advantage - range of intelligence
Size comparison (vs animals)
- Absolute brain mass != intelligence
- Encephalisation quotient: log brain mass / log body mass
Subcortical
-
Thalamus
- Gateway for sensory (except smell)
** Tongue -> gustatory cortex
** Visual -> lateral geniculate nucleus -> primary visual cortex
** Sound -> medial geniculate nucleus -> auditory cortex
** Touch/pain/pressure/temp -> primary somatosensory cortex
- Spatial processing & spatial/non-spatial memory
e.g. rats & smell order (sequence memory)
Hypothalamus
- Fight/flight/feed/mate
- Hormones & ANS - homeostasis (temp, weight, emotion)
e.g. cats & rats, starvation & aggression
Amygdala
- Relevance detector
- Threat detection & fear
- Fight (aggression) or flight
e.g. S.M. showed no fear
Hippocampus
- Memory encoding & consolidation
- Spatial processing
e.g. H.M. - anterograde amnesia
Basal ganglia
- Nuclei: globus pallidus (mvt), caudate nucleus, putamen, subthalamic nucleus, substantia nigra (mvt), nucleus accumbens (reward)
- Motor control - planned & spontaneous movement
e.g. Parkinson's Disease
- Reward - dopamine release
e.g. rats self-stimulating
- Memory, emotional expression