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DNA vaccines - Coggle Diagram
DNA vaccines
diffirent
Approach
genetic material from the virus or bacteria is used to
elicit an immune response
process
isolate a gene from the target parthogen
spilice the gene into double vector
the plasmid can be replicated and purified
the vaccine is ready to be injected
DNA vaccine in human bodies
build long-lasting immunity
prompt helper T cells and B cells to multiply
B cells to multiply and create memory cells and activate cytotoxic "killer" T cells
much safer than a live-virus vaccine
DNA vaccine plasmids are not living
thus nonreplicating
no risk that they may cause an illness
DNA vaccine is in clinical trials
advantage
well tolerated by patiens
cost effective
hamped
low a level of immunogenicity
disrupt cellular processes
produce anti DNA antibodies
developed a lot in the past few years
The pathogens that are attenuated or destroyed are not relevant
induce a strong cellular response and build a strong humoral or antibody response
against the toughest pathogens