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Humoral response (antibody-mediated immunity) Berk Boyko Alex, immune…
Humoral response (antibody-mediated immunity)
Berk
Boyko
Alex
Mediated by
Antibodies
Method of removal
Antibody-mediated destruction
Neutralize in 3 ways
Mark the pathogen for uptake by macrophages
Bind to the pathogen, preventing it from binding to the cells
Preventing bacterial toxins from entering cells
Macromollecules
secreted antibodies
complement proteins
some antimicrobial peptides
Driven by
(main cells)
B-cells
Differentiate into plasma cells
Produce antibodies
activated by helper T-cells
Site of activity
Extracellular fluid
Speed of response
Fast response
Method of detection
MHS II receptors
Extracellular antigens
Extracellular antigens
