Please enable JavaScript.
Coggle requires JavaScript to display documents.
fatty acid catabolism, lipid biosynthesis - Coggle Diagram
fatty acid catabolism
ketone bodies from the liver
acetone
acetoacetate
D-beta-Hydroxybutyrate
fatty acid oxidation occurs in three stages
beta oxidation
each pass removes one acrtyl moiety in the form of acetyl-CoA
citric acid cycle
respiratory chain
fatty acids are absorbed in small intestine
hormones trigger mobilization of stored triacylglycerols
large fatty acids are transported via acyl-carnitine/carnitine transporter
fats provide efficient fuel storage
glycerol enters glycolysis
lipid biosynthesis
fatty acid synthesis
condensation of growing chain with acetate
reduction of carbonyl to hydroxyl
dehydration of alcohol to trans-alkene
reduction of alkene to alkane
ACP serves as a shuttle in fatty acid synthesis
contains a 4-phosphopantetheine
delivers acetate or malonate to fatty acid synthase
shuttles growing chain from one active site to another
acetate used in lipid biosynthesis comes from malonate
malonyl-CoA is formed from acetyl-CoA and bicarbonate
fatty acid synthase
