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CH16 The Citric Acid Cycle - Coggle Diagram

- - - - Step1:C-C Bond Formation by Condensation of Acetyl-CoA and Oxaloacetate
        
        Citrate Synthase
      - Step2:Isomerization by Dehydration/Rehydration
        
        Aconitase
      - Step3;Oxidative Decaroxylation by Isocitrate Dehydrogenase
      - Step4:Final Oxidative Decarboxylation by a-Ketoglutarate Dehydrogenase
        
        a-Ketoglutarate Dehydrogenase
      - Step5:Genration of GTP Through Thioester:Substrate-Level Phosphorylation by Succinyl-CoA Synthetase
        
        Succinyl-CoA synthetase
      - Step6:Oxidation of an Alkane to Alkene by Succinate Dehydrogenase
        
        Succinate Dehydrogenase
      - Step7:Hydration Across a Double Bond:Fumarase
        
        Fumarase
      - Step8:Oxidation of alcohol to a Ketone and Regeneration of Oxaloacetate by Malate Dehydrogenase
        
        Malate Dehydrogenase
      - Other information about CAC
        
        One turn of the citric acid cycle
        
        Net result of the citric acid cycle
        
        CAC intermediates are ampjibolic
        
        Regulation of the citric acid cycle
        
        Inhibitors:NADH and ATP
        
        Activators:NAD+ and AMP
  - - - Structure of Lipoyllysine
      - Pyruvate Dehydrogenase Complex(PDC): A large (up to 10MDa)multienzyme complex located on the innermembrane of mitochondria including E1(pyruvate dehydrogenase),E2(dihydrolipoyl transacetylase),E3(dihydrolipoyl dehydrogenase)
        
        Reaction
        
        Enzyme2:
        
        Enzyme3:
        
        Enzyme1:
      - Structure of Coenzyme A(=CoA)