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INFECTIVE KERATITIS, image, LOGO MSU, image, Prepared by:
Nur Ainaa…
INFECTIVE KERATITIS
INTRODUCTION
An infection that develops in the cornea is called infectious keratitis, which is very rare in a healthy eye. An ocular infection can only occur when the ocular defenses have been compromised. This infection can affect contact lens wearers and sometimes people who do not wear contact lenses, trauma (accidental injuries), ocular surface disease, and other factors. It may cause blindness if left untreated
CAUSATIVE AGENTS
P.aeruginosa
Gram-negative bacillus (rod) that fluorishes in soil, vegetation and moist situations in the hospital environment.
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S. aureus
Common Gram-positive and coagulase-positive commensal of the nares,skin and conjunctiva.
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SIGNS & SYMPTOMS
SIGNS
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SYMPTOMS
Ocular pain, photophobia, blurred vision, foreign body sensation and discharge.
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TREATMENT
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Antibiotic dual therapy
- combination of two fortified antibiotics
- aminoglycoside & cephalosporin
- cover gram-positive & gram-negative pathogens
- not commercially available
- must be specially prepared
REFERENCES
1.Dea L, Lewis J, Sharma A. The pharmacist’s role in managing microbial keratitis. US Pharm. 2018 Jul 13.
- Wong, R. L., Gangwani, R. A., Yu, L. W., & Lai, J. S. (2012). New treatments for bacterial keratitis. Journal of Ophthalmology, 2012, 1–7. https://doi.org/10.1155/2012/831502
- Salmon, J. F., & Kanski, J. J. (2020). Kanski's clinical ophthalmology: A systematic approach. Elsevier.
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Prepared by:
- Nur Ainaa Binti Zulkifli (012021091174)
- Nadia Amirah Binti Mohd Arifin (012020021922)