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INFECTIVE CORNEAL ULCER, CAUSATIVE AGENTS ?, SYMPTOM, SIGN, Unknown,…

- - - - Moxifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell replication.
    - - GANCICLOVIR
        
        Ganciclovir's antiviral activity inhibits virus replication. This inhibitory action is highly selective as the drug must be converted to the active form by a virus-encoded cellular enzyme, thymidine kinase (TK). TK catalyzes phosphorylation of ganciclovir to the monophosphate, which is then subsequently converted into the diphosphate by cellular guanylate kinase and into the triphosphate by a number of cellular enzymes.
      - FUNGAL
        
        NATAMYCIN
        
        Blind sterol in fungal membranes
        
        AMPHOTERICIN
        
        ACANTHAMOEBA
        
        KETOCONAZOLE
        
        For itraconazole and keratoconazole , it works principally by inhibiting the fungal enzyme P450 which depedent on lanosteral 14-α-demethylase. When this enzyme is inhibited it blocks the conversion of lanosterol to ergosterol, which disrupts fungal cell membrane synthesis.
        
        ITRACONAZOLE
- - - - COLD COMPRESSION ON THE EYE
- - - - Contact lenses or steroid eye drops used improperly can induce fungal infections, which can lead to corneal ulcers. Fungal keratitis can also be caused by a corneal injury that results in plant material seeping into the eye.
      - Acanthamoeba
        
        Acanthamoeba is a single-celled, tiny amoeba that may infect humans. In both fresh water and soil, they are the most frequent amoebae. When Acanthamoeba penetrates the eye, it can cause a serious infection, especially in those who wear contact lenses.
- - - - Tobramycin 15mg/mL
      - Cefazolin 50mg/mL
    - - VIRAL INFECTION
        
        Trifluridine 1% drops
        
        Ganciclovir 0.15%
        
        Valacyclovir 1000mg
        
        Acyclovir 400mg
        
        ACANTHAMOEBA INFECTION
        
        TOPICAL
        
        ORAL
        
        Ketoconazole 400 mg
        
        Itraconazole 400 mg
        
        Propamidine 0.1%
        
        Neomycin 0.175%
        
        Polyhexamethylene biguanide 0.02%
        
        1 more item...
      - Topical Antifungal
        
        Natamycin 5%
        
        Amphotericin B 0.15%
        
        Voriconazole 1%
      - ORAL
        
        Voriconazole 400 mg
        
        Ketoconazole 400 mg
        
        Fluconazole 400 mg
        
        Itraconazole 400 mg