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Reflection of Lesson 1-12 - Coggle Diagram
Reflection of Lesson 1-12
Central Dogma ODE Model
ODE used to model Central Dogma
DNA transcribe to RNA
RNA translate into protein
Activation Hill Function
One gene facilitates expression of other gene
Example: Gene1 (G1) use to activate Gene2 (G2)
Model the interaction using Hill Function
Repression Hill Function
Model using Hill Function
One gene represses expression of other gene
Example: Gene1 (G1) represses Gene2 (G2)
Oscillating Gene Network
Made up of 3 genes
With activation cascade
Negative feedback loop
Oscillating gene: expressed in a rhythmic pattern or in periodic cycles
Deterministic vs. Stochastic
Deterministic
Give precise answer for a given set of inputs
Stochastic
Provides data and probability outcomes that account for various amounts of unpredictability / randomness
Gillespie Algorithm
Famous method of stochastic simulations
Computer oriented procedure for simulating the changes on molecular populations
For chemical species in a chemically reacting system
