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Innate immune system part A - Coggle Diagram
Innate immune system part A
Structure
Primary lymphoid organs
Bone marrow and thymus
Generation and maturation
Secondary lymphoid organs
Spleen
Lymph nodes
Peyer's patches
MALT
Lymph system
Network of vessels
Drain excess fluid
Thoracic duct
Bone marrow
Erythrocytes
Leukocytes
Granular
Neutrophils
Basophils
Least abundant
Cytokines
Heparin
Mast cells
Eosinophils
Parasites
Inhibits cytokines
Agranular
T cells
B cells
NK cells
Monocytes
Platelets
Haematopoiesis and differentiation
Myeloid progenitor
Neutrophils
Basophils
Eiosinophils
Monocytes
Megakaryocyte
Platelets
Erythroblast
Erythrocyte
1st line defence
Keratinised skin
Low pH
Impermeable
Mucous membrane
Cavities
Traps foreign particles
Mechanical removal
Secretions
Flushing action
Microcidal factors
Directly damage
Microbiota
Mutualism
2nd line defence
Phagocytosis
Engulfment
Soluble chemical factors
Destruction
Phagocytic cells
Monocytes-derived
Macrophages
Mitochondria
Anti-microbial secretions
Basement membrane
Phagocytosis
Polymorphonuclear
Small
Neutrophils
Abundant
1st at infection site
No mitochondria
Glycogen stores
Phagocytosis
Attaches (receptors)
Pseudopodia
Lysosomes fuse
Killed (microcidal mechanisms)