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DNA VACCINES 22 - Coggle Diagram
DNA VACCINES 
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how to create?
isolate a gene from the
target pathogen, then splice the viral gene into a double-stranded DNA vector.
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clinical trials
They may disturb biological processes and generate anti-DNA antibodies, resulting in immunogenicity levels that are too low.
a cellular level when DNA vaccines enter the body
On a cellular level, once injected, DNA vaccinations prompt helper T cells and B cells to multiply and produce memory cells, as well as activate cytotoxic “killer” T cells, which are the toughest pathogen fighters.
the result: This type of dual cellular and humoral response gives long-lasting immunity, similar to what most live attenuated vaccines achieve
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disadvantage
disrupt cellular processes and produce anti-DNA antibodies, resulting in too low a level of immunogenicity, means that they are not effective enough.
market research
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