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Live Attenuated Vaccines and Inactivated Vaccines - Coggle Diagram
Live Attenuated Vaccines
and Inactivated Vaccines
Inactivated Vaccines
Definition
a vaccine created by reducing the virulence of a pathogen
How to create?
Inactivated vaccines are not produced with a living virus. Scientists use chemicals, heat, or radiation to render apathogenic virus harmless, or "fixed."
Can prevent
Hepatitis A and rabies
Pros and Cons
Pros
Creating a strong immunity to a disease
Can be reconstituted and easily stored
Providing the most resistance against the disease.
Cons
Deliver a much weaker immune system response
Must be refrigerated or they are rendered unstable
Their strength tends to lead to a lower level of safety when compared with fixed-virus vaccines
Live Attenuated Vaccines
How to create?
Use a nonpathogenic virus
related to the real pathogen
Involving physicians weakening the virus in a laboratory, purifying the vaccination solution, and administering the vaccine orally or by injection
Can prevent
Measles, mumps, and rubella
Definition
Vaccines are made from living, weakened viruses
and from dead viruses
Pros and Cons
Pros
Live attenuated virus vaccines also create a stronger immunity to a disease than inactivated vaccines
Live attenuated vaccines typically provide better protection against illnesses
Cons
Perishable live-virus vaccines
Quite potent
Lead to a lower level of safety