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Live Attenuated Vaccines and Inactivated Vaccines - Coggle Diagram
Live Attenuated Vaccines
and Inactivated Vaccines
Inactivated Vaccines
definition
made from dead viruses
how to create
Scientists use chemicals, heat, or radiation to render a pathogenic virus harmless, or “fixed”
diseases that can be prevented
hepatitis A and rabies
pros and cons
cons
weaker immune system than live attenuated vaccine
can be reconstituted and easily stored
pros
they require several additional doses
a lower level of safety when compared with fixed-virus vaccines
mutate back to its original, virulent form and cause a true infection
not recommended for individuals with compromised immune systems
Live Attenuated Vaccines
diseases that can be prevented
measles, mumps, rubella, smallpox virus
how to create
use a nonpathogenic virus related to the real pathogen
physicians weakening the virus in a laboratory, purifying the vaccination solution, and administering the vaccine orally or by injection.
pros and cons
pros
create a stronger immunity to a disease
cons
lab-produced live attenuated vaccines must be
refrigerated or they are rendered unstable.
not easy to provide to lower-income nations where refrigeration devices are not abundant
definition
made from living, weakened viruses