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Topical drugs of nose - Coggle Diagram
Topical drugs of nose
Oxymetazoline
Contraindications
- high blood pressure
- diabetes
- coronary artery disease
- enlarge prostate
- closed angle glaucoma
Side effects
- Burning
- stinging
- nausea
- sneezing
- dizziness
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Mechanism of action
Binds to and activate alpha 2- adrenergic receptors for constrict arterioles of the nose to decrease nasal congestion
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Phenylephrine
Contraindications
- Overactive thyroid gland
- Heart attack
- High blood pressure
- Partial heart block
- Coronary artery disease
Side effects
- Trouble sleeping
- Mild upset stomach
- Fast heart beat
- Shaking
- Dizziness
Indications
Increase blood pressure in adults with clinical significant hypotension results primarily vasodilation
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Xylometazoline
Contraindications
*Overactive thyroid gland
- high blood pressure
- diabetes
- abnormal EKG with QT changes from birth
Side effects
- wheezing
- dizziness
- blurred vision
- headache
- pounding heartbeat
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Mechanism of action
Activates a-adrenergic receptors leads to vasoconstriction of blood vessels of nasal mucosa resumption of nasal airflow
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