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Computational methods for collagen imaging visualization enhancement -…
Computational methods for collagen imaging visualization enhancement
Multimodal image registration
The need for registration
Scale: Different scale provides comprehensive views of collagen fibers
Modality
Modality: Other non-collagen specific imaging modalities give a context of tissue microenvironment
Collagen imaging modalities can reveal different properties of collagen
Difficulties for registration
Large difference in the visual appearances
Few mutual information, nonlinear relation between the feature descriptors
Some methods
Hybrid methods
Latent representations
Image synthesis
Some representative work
Image pairs with pixel-wise correspondences
Unpaired image synthesis
Why image synthesis plays a role
Clinical compatibility
Compatible with clinical workflow
Slide screening
Decide which ones go to actual complex stain and imaging
Low-cost
Avoid potential sample damage
A proxy task for multimodal image registration
Limitation
Image stitching