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Immune System
Maria Chuc Garcia
P.1, Adaptive
Third-line of Defense…
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Adaptive
- Third-line of Defense
attacks foreign substances, takes longer than innate
- defenses
Humoral immunity (B cells) cellular immunity (T-cells)
- Specific defense system
- ELIMINATES pathogens and abnormal cells
- Characteristics
- Specific: recognizes & targets specific targets
- Systemic: Not restricted to initial site
- Memory: Even STRONGER attack
Antibodies
- Immunoglobulins(Igs) Proteins secreted by plasma cells
-Can bind specifically with antigen detected by B cells
- Groped into one of 5 Ig classes
- Basic Antibody Structure
- T and Y shaped antibody monomer: 4 Lopping polypeptide chains
- Antibody clasesses
IgM, IgA, IgD, IgG, IgE
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3rd Line of Defense
- Attacks foreign substances but takes longer
- Humoral Immunity
- B cells
- Cellular Immunity
- T Cells
2nd line of defense
(Internal Defenses)
- Phagocytes
-Natural Killer Cells
- Inflammation
- Antimicrobial Proteins
- Fever
Passive Immunity
- Occurs when ready-made antibodies are introduced into body
- B cells not challenged by antigens, memory does not occur
- Protection ends when antibodies degrade
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Passive Immunity
Naturally Acquired
- Antibodies passed from mother to fetus vil placenta: or to infant in her milk
Artificially Acquired
- Injection of exogenous antibodies (Gamma Globulin)
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Celluar Response
- reactive T cells is required for immunity,
- T cells, together with B cells, form the adaptive immune response to viral infections.
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Lymphatic System
- maintains fluid levels in our body tissues by removing all fluids that leak out of our blood vessels.
- optimal functioning of our general and specific immune responses.
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