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CHOLINERGIC STIMULANTS - Coggle Diagram
CHOLINERGIC STIMULANTS
Mechanism of action
The parasympathetic nerve regulates the function of various organs and glands and, like all choline mimetics, primary uses acetylcholine as its major neurotransmitter.
Anticholinesterase drugs are drugs that inhibit cholinesterase, protect acetylcholine from hydrolysis, and produce cholinergic effects. Anticholinesterase are further classified into reversible and irreversible agents.
Muscaruric receptors are present in the parietal cells of the stomach and in the central nervous system.
depending on the type of receptor that is meditated, the peripheral action acetylcholine is classified as acting on muscarinic or nicotinic receptors.
Indication of the drug
Acute colonic pseudo-obstruction: Off-label use of neostigmine is acute pseudo occlusion of the colon.
Neostigmine is a common option for both prevention and treatment of urinary dilation and retention. Bethanechol is an indication for acute postoperative and partum non-obstructive urinary retention.
cholinesterase inhibitors such as rivastigmine, donepezil, and galantamine are drugs that can be used for cognition and overall function in patients with dementia of any cause.
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Storage conditions
must be stored, unopened in temperature's of 4 to 25 degrees celcius and must be prevented from freezing.
Route of mechanism
For myasthenia gravis, pyridostigmine dosing is oral.
Pilocarpine and physostigmine, when used as a miotic agent, the route of mechanism is via ophthalmic eye drops.
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Definition
They are known as drugs that operate on the neurotransmitter acetylcholine,
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