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Gigantism Gigantism, nursing diagnosis, signs and symptoms, nursing care…
Gigantism 
defination
occurs when the growth hormone hypersecretion occurs before the fusion of the long bone epiphysis and is characterized by a toe statue
pathophysiology
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it is secreted in the pulsatile manner, 4 to 11 pulses in a day. due to this pulsatile nature of secretion measurement of random growth hormone levels are not useful.
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growth hormone releasing hormone stimulates the release of growth hormone from the pituitary. GHRH containing neurons are mainly seen in the arcuate nucleus and ventromedial nucleus.
somatostatin which is also secreted from the hypothalamus exert an inhibitory action on the secretion of GH
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GH stimulate the synthesis of IGF-1 from the liver. IGF-1 is a seventy amino acid protein that is similar to insulin. beside post-receptor signaling mechanisms involving tyrosine kinase and insulin receptor substrate-1 (IRS-1) are also similar for IGF-1 and insulin
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encourage in involvement in extramural activities.
.offer emotional support to the patient.
.encourage patients socialization with environmental factors
.disturbed self perception related to growth of body parts as evidenced by amplified hands feet and jaw
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references
references
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Gigantism and acromegaly ; practice , essential , background and pathophysiology . 2017-01-07
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diet therapy
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choose low fat , low salt low sugar options
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