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PULSE MAG - Coggle Diagram
PULSE MAG
CELLULAR
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movement of electrons affects cellular physiology by causing ions to move towards electrodes which affects the physiology of the cell, this creates an opening of the calcium voltage gates, flooding the cell with calcium
the influx of calcium in the cell leads to increase of calcium- calmodulin binding, when calcium binds to calmodulin, NO is released leading to therapeutic effects, in addition the calcium-calmodulin can bind to calmodulin dependent portion kinase which increases cellular function
triggering of all this will rapidly reduce the production of pro-inflam factors and increase the production of messenger cells ro drive the release of messenger cells to drive the release of growth factors that support neovascularization, tissue regeneration and remodelling
VASOCONSTRUCTION
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damage to the cell membrane allows intracellular fluid to escape, if damaged the cell membrane can not close quick enough which leads to distruption in the cell and the cell will be unable to function and die. the ability to avoid cellular death is to aid in total healing because the cells can not leave and will not need to be relaced
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activation of the cell membrane adenosine receptor by endogenous adenosine associated with reduction of prostaglandins and inflammatory cytokins
BONE HEALING
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the small current increases the osteoblast expression to the area initiating depolarisation of toe, mimicking the initial phases of fracture prepare, emanating wolfs law and promoting osteogenesis and promoting differentiation of osteoblasts to encourage ossification
increases the structural intensity of bone and cartilage extra-cellular matrix by enhancing repair and altering homeostatic balance of signalling, producing anti-inflame effects
signal transduction through adenosine cell membrane receptors causes building effects on bone and cartilage matrix with a breaking effect on the inflamation of the joints
VASODILATION
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NO causes dilation of the capillary spinchter that increases blood blow= increased O2 and nutrients to the injury site, re-establishing the injured cell membrane
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PAIN RELIEF
NO pathway decreases pain and alters neurotransmitters in the brain via the opioid system: hormones.
Electromagnetic field distrust the brains ability to transmit pain by decreasing the nerve cell potential from normal -70mV to -90mV; the voltage is too low so the synapse can't release of chemical transmitters to pass on the pain sensation, affects c-fibres