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Cell Division/Disease - Coggle Diagram
Cell Division/Disease
Mitosis
Prophase(chromosomes condense ,spindle fibers form, nuclear membrane and nucleolus disappear)
Metaphase((chromosomes line up at the equator of the cell)
Anaphase(sister chromatids separate)
Telophase (nuclear membrane reforms, chromosomes unwind)
Cytokinesis(Cell division)
Cell Cycle
G1 (grows/Ready's for chromosome duplication
G1 Check point
S phase (Chromosomes duplicate
S phase check point
G2 (Cell prepares for M phase my making microtubules/other proteins)
G2 Cheackpoint
M Phase (Cell division)
M phase cheackpoint
Cancer
Risk Factors
Heredity
smoking
smokeless tobacco
chemical exposure
Human papillomavirus
sun exposure
Mutated cancer regulation genes
Mutated tumor suppressor genes
Proto oncogenes
DNA
DNA Replication
Helicase unzips DNA
DNA polymerase adds new nucleotides to old strand with base pairing rule
RNA primer is used in opposite DNA strand
Ligase zips DNA back together
Mutations
Insertion
Deletion
Substitution
Cyclins/CDKs
Cyclin levels go up
CDK binds with enough cyclins to start next phase of cell cycle
Cyclin breaks down towards end of phase
CDK levels stay the same
Telomeres
They are caps on chromosomes
Hayflick limit
Telomeres shorten each cell division
40-60 divisions
Telomeres are too short to divide