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adrenergic stimulants - Coggle Diagram
adrenergic stimulants
epinephrine
indication
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stimulates the heart rate, improves breathing, reverse hives and reduce swelling of the face, lips and throat
mechanism of action
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relaxes smooth muscle of the bronchi and iris and is a histamine antagonist, rendering it useful in treating the manifestation of allergic reaction and associated condition
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side effect
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fast, irregular or pounding heartbeat
dopamine
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indication
used to treat certain conditions that occur when you are in shock, which may be caused by heart attack, trauma, surgery, heart failure, kidney failure, and other serious medical conditions.
salmeterol
mechanism of action
stimulate intracellular adenylate cyclase, an enzyme that catalyzes conversion of adenosine triphosphate to cyclic adenosine monophosphate. increased cAMP levels relaxes bronchial smooth muscle and inhibits release of mediators hypersensitivity
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route of administration
patient is instructed to open and prepare mouth peace of diskus device and slide device lever to activate first dose
indication
Salmeterol is a long-acting b2 adrenergic receptor agonist used in the maintenance and prevention of asthma symptoms and maintenance of chronic obstructive pulmonary disease symptoms
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albuterol
indication
used to treat difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness caused by lung diseases such as asthma and chronic obstructive pulmonary disease
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storage
room temperature, away from heat and light
mechanism of action
Albuterol acts on beta-2 adrenergic receptors to relax the bronchial smooth muscle. It also inhibits the release of immediate hypersensitivity mediators from cells, especially mast cells.
references
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Manara A, Hantson P, Vanpee D, Thys F: Lactic acidosis following intentional overdose by inhalation of salmeterol and fluticasone. CJEM. 2012 Nov;14(6):378-81. doi: 10.2310/8000.2012.110581
Berridge KC, Robinson TE: What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res Brain Res Rev. 1998 Dec;28(3):309-69.
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