Nitrofurantoin is a well-known medication to clinicians with a tolerable side effect. A well-known eradicator of E. coli, nitrofurantoin, is otherwise less active against other Gram-negative rods such as Klebsiella and Pseudomonas.[8] Although their incidences are rare, ordering physicians must keep in mind the possibility of detrimental, but rather infrequent, risk of pulmonary fibrosis and interstitial pneumonitis, especially in predisposing patients such as those with chronic obstructive pulmonary disease