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Explanations Part One - Coggle Diagram
Explanations Part One
Background
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Appears to lie with the brain neurochemistry and dopamine. Nicotine heightens dopaminegergic activity. And as a reuslt, tends to become additive.
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Gluatamamte and GABA
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Nicotine causes glutamate to speed up dopamine relapse, but also prevent GABA from slowing it down after dopamine levels have been raised.
This combination of dopamine releases and the inhibition of GABA results in increase in dopamine and amplification of rewarding properties of nicotine.
MAO
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Blocking MAOreuslts in even higher dopamine levels, strengthening the smoking habit by maintaining feelings of pleasure.
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