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Biomed Building, TISSUE ENGINEERING, REGULATORY AFFAIRS, MEDICAL IMAGING,…
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TISSUE ENGINEERING
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Biomaterials
Metals
Disadvantages: Corrosion, metal ion toxicity
Advantages: Strong, wear resistant and easy to sterilise
Bioceramics
Advantages: Corrosion resistant, bioactive, easy to sterilise
Disadvantages: Easy to break, hard to fabricate
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Polymer
Advantages: Tailorable physically, biodegradable, easy to fabricate
Disadvantages: Leachable toxic compunds, wears, hard to sterilise
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REGULATORY AFFAIRS
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ISO13485
Quality Management System, dictated by the International Standards Organisation. Consistent around the world
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MEDICAL IMAGING
STRUCTURAL IMAGING
CT SCANNING
Computed Tomography - Uses a rotating x-ray tube with a fixed detector to measure transmission through an object. Many of these data points are then used to 'map' an image.
FUNCTIONAL IMAGING
PET IMAGING
RatCAP Article - Experiment in which a PET scanner was placed on the heads of rats to allow for imagine while awake, rather than under anaesthesia
Uses radioactive nuclides which emit positrons (e.g. C-11 or O-15). As these positrons collide with electrons, they emit gamma rays 180 degrees from one another. These emissions are then recorded and mapped using electronic collimation.
SPECT IMAGING
Single Photon Emission CT - Uses a radioactive substance that emits a single gamma ray. Many of these emissions are used to 'map' an image of the object being scanned.
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NANOTECHNOLGIES
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Passive Targeting
Picks out gaps in blood vessels, thus swimming past 'normal' vasculature and killing tumours
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Biosensing and Imaging
Nanoparticles can be used to detect morphology of biological matter, often by using fluorescent nanoparticles
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