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Leishmaniasis, Leishmania life cycle - Coggle Diagram

- - - - also called Kala-azar
    - - most common form
  - - - Promastigotes are phagocytized by macrophages
        
        Promastigotes transform into Amastigotes inside macrophages
        
        Amastigotes multiply in cells (including macrophages) of various tissues
        
        Sandfly takes a blood meal (ingest macrophages infected with Amastigotes)
        
        Ingestion of parasitized cells
        
        Amastigotes transform into Promastigote stage in midgut
        
        1 more item...
    - - Aflagellar stage
      - occurs in vertebrate host
      - Round or oval shaped
      - nucleus relatively larger
    - - Flagellar stage
      - occurs in the sandfly
      - spindle shaped
      - Nucleus smaller
- - - - non palpable
        
        Freckles
        
        Moles
    - - Elevated
        
        Nevi
        
        Warts
        
        Insect bites
        
        Acne
    - - Subcutaneous growth
        
        cysts
        
        lipoma
        
        Fibromas
    - - clear blisters usually less than 1 cm
        
        herpes infections
    - - clear blisters usually more than 1 cm
        
        Friction
        
        contact dermatitis
        
        drug reactions
    - - opaque vesicles (pus filled)
        
        Acne
        
        Impetigo
        
        Boils
    - - Irregular-shaped, solid, elevated area
        
        Allergic reactions
        
        Hypersensitivity to drugs, stings or bites
        
        Urticaria/ Hives
  - - - Caused by scratches, cuts, and scrapes
        
        keloids
    - - caused by aging, topical corticosteroids, and poor circulation
        
        Lupus Erythmatosus
        
        Cutaneous T-cell lymphoma
    - - Caused by physical trauma or bacterial infection.
    - - Breaks in the skin that go deep (Sometimes even to the second layer)
    - - Can form from dried serum, blood, or pus over the irritated skin
    - - Built up horny epithelium cells
        
        psoriais
    - - Thickining of the normal skin (with normal markings intact) due to overscratching or rubbing
- - - - destruction of mucous membrane
    - - fever
      - weight loss
      - anemia
      - hepatosplenomegaly
    - - multiple skin sores
      - swollen glands