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Renal Physiology 2 - Coggle Diagram
Renal Physiology 2
Regulatory mechanisms
Autoregulation / Myogenic feedback
Pressure response
Response =
afferent
arteriole constriction
:arrow_down: RBF and GFR
Tubulogenic Feedback Mechanism
Salt conc. detection @ macula densa
Response: afferent arteriole constriction
:arrow_down: RBF & GFR
Regulation of GFR
Afferent Regulation
Constriction
:arrow_down: RBF and GFR
:arrow_down: Capillary pressure
Dilation
:arrow_up: RBF and GFR
:arrow_up: Capillary pressure
Vasoconstrictors
Norepinephrine and epinephrine
Dopamine
Endothelin
Angiotensin
Vasodilators
Prostaglandins
Nitrous Oxide (NO)
Bradykinins
NPs
Efferent Regulation
Constriction
:arrow_up: capillary pressure and GFR
:arrow_down: RBF
Dilation
:arrow_down: Capillary pressure and GFR
:arrow_up: RBF
Glomerular Filtration Pressures
GFR = Kf x Pnet
Pnet
Capillary
Hydrostatic pressure (Favour filtration)
Oncotic pressure (Favour absorption)
Bowman's Space
Hydrostatic pressure (Favour absorption)
Oncotic pressure (Favour filtration)
Kf = ultrafiltration coefficient