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B-cells, macrophages, dendritic cells - Coggle Diagram
B-cells, macrophages, dendritic cells
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Dendritic cells
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Function as an APC (antigen-presenting cell), acting as a link between innate immunity and acquired immunity.
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Present in tissue that is in contact with the external environment, such as skin and mucosa. It can also be found in an immature state in the blood.
In the skin and mucosal tissue such as the oral mucosa, there is a specialized dendritic cell type, a Langerhans cell (LC), which contains large cell organelles called Birbeck granules.
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Due to the thin epithelium with the microcirculation nearby of the sublingual oral mucosa, it provides a useful route of entry for drugs and allergens during desensitization therapy by way of the numerous Langerhans cells.
At certain developmental stages, it grows branched projection or dendrites that are similar in appearance but distinct from the dendrites of neurons.
Once activated, it migrates to the lumph nodes or other lymphoid tissue, where it interacts with T cells and B cells to initiate and shape the acquired immune response.
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B cells
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When stimulated by an antigen, it travels to the source of injury
TWO MAIN TYPES
Plasma Cell
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Round, pinwheel shaped nucleus and visible cytoplasm
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