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Tobacco Cessation, These effects include central and peripheral nervous…

- - - - Dosing is based on cigarettes smoked per day:
        
        more than 10 cigs/day:
        Step 1: 21mg/day: Weeks 1-6
        Step 2: 14mg/day: Weeks 7-8
        Step 3: 7mg/day: Weeks 9-10
        
        <10 cigs/day:
        Step 2: 14mg/day: 6 weeks
        Step 3: 7mg/day: 2 weeks
      - Duration: 10 weeks
      - Patch can be worn for up to 24 hours per day. Rotate patches to avoid skin irritation
      - Various, 7-21 mg every 24 hours
    - - Duration: 12 weeks
      - Allow the lozenge to dissolve slowly, approximately 20-30 minutes
      - Do not eat or drink anything 15 minutes prior to or during lozenge use
    - - Duration: 12 weeks
      - Continuous use can lead to adverse effects (pyrosis, nausea, hiccups)
      - Do not eat or drink 15 minutes before or during use of gum
      - 2-4 mg gum prn, up to 24 pieces daily
    - - 2nd line:
        nortriptyline (up to 75-100 mg QD) (contraindication with using monoixidase inhibitors for 14 days prior because it inhibits the reuptake of 5-HT and NE)
        clonidine (0.15 -.75mg)