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Psychofarmology - College 5 - Coggle Diagram

- - - - Medication: block Dopamine D2 receptors. Decrease psychotic symptoms by decreasing DA reactivity.
    - - Postsynaptic actions:
        
        D1 like receptors (D1 & D5, these are stimulating/excitatory)
        
        D2 like receptors (D2, D3, D4, these are inhibiting)
        -> Adenylate cyclase synthesizes cAMP
      - Presynaptic actions:
        
        Dopamine autoreceptors
        D2 like receptors, (D2 and D3)
      - Primary pharmacological property = D2 receptor antagonism. it is working against the action of dopamine. Changes dopamine reactivity, antipsychotic actions. But also side effects.