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Chronic Obstructive Pulmonary Disease COPD, Salbutamol sulphate,…

- - - - shortness of breath on exertion, progresses to occurring at rest
      - little sputum presented when coughing
      - clubbed fingers
      - tachypnea with prolonged expiration and use of accessory muscles
      - hyperinflation eventually leads to development of "barrel chest"
      - anorexia
      - frequent infections due to secretions being more difficult to remove
    - - Genetic factors for nonsmokers, typically low alpha-antitrypsin protein
      - exposure to air pollutants
      - cigarette smoking
- - - - increased levels of cAMP causes bronchial smooth muscle to relax
        
        leading to bronchial dilation and increased airflow