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method validation - Coggle Diagram

- - - - repeatability
        
        express the precision under the same operation conditions over short interval of time
        
        should be assessed using minimum 9 determinations
      - intermediate precision
        
        express within-laboratory variation in terms of standard deviations,relative standard deviation and confidence interval
        
        depends on circumstance
      - reproducibility
        
        ability to produce data within the predefined precision
  - - - determined by the analysis of sample with know concentration of analyte and establishing the min level
    - - exhibit background noise, which is to compare measured signals from sample with know low concentration of analyte with those of blank sample
  - - - different laboratories
      - different analysts
      - different instruments
      - different reagents
      - different days