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THE SMALL RNAs WORLD - Coggle Diagram

- - - - Repress gene expression through post-transcriptional gene silencing in land plants.
      - 21-nucleotide-long RNA duplexes with overhangs incorporated into an RNA-Induced Silencing Complex (RISC)
      - TAS1, TAS2 and TAS4 require one miRNA binding site for cleavage to occur; TAS3 requires two binding sites
    - - DCL3-dependent
      - DCL1-dependent
  - - - miR156 and miR172
        
        Target in the 3' UTR of SPL
        
        mi156 are high in the juvenile phase
        
        mi156 promotes degradation; mi172 controls the flowering
      - lin-14 and lin-4
        
        Post-transcriptional kind of regulation
        
        Lin-14 has different binding sites for lin-4
        
        In wt lin-14 is regulated by lin-4
    - - miR399
        
        Target a pathway of E2, involved on phosphate accumulation factors
        
        Its expression is induced by phosphate starvation
        
        E2 is an ubiquitination factor highly complementary to miR399
        
        Pho2 is the E2 loss-of-function mutant
        
        It is able to move from the shoot to the root
        
        miR399 also partial anneals with IPS1