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Inflammation and fever, Early response to lesion Brief, prior to immune…

- - - - Monocytes
        
        Monocytes (blood) -> Macrophages (tissue)
        
        Largest phagocytic cells
        
        Life three times greater than granulocytes
        
        Collaborate in the destruction of the causative agent of the infection
      - Granulocytes
        
        Neutrophils
        
        1st to reach the region
        
        Granules that contains enzymes = degrade phagocytize particles
        
        Produce hydrogen peroxide
        
        Release by bone marrow, have 1/2 life (10h)
        
        During infection = large amount = leukocytosis
        
        Eosinophils
        
        Allergic reactions and infections by parasites
        
        Granules contains toxic protein against large parasites that cannot be phagocitized
        
        Basophils
        
        Allergic reactions
        
        Granules contains histamine
- - - - Immunologic response → inflammation
    - - Acute
      - Chronic